MME anticorps

N° du produit ABIN120746

L’anticorps Souris Monoclonal anti-MME a été validé pour FACS. Il convient pour détecter MME dans des échantillons de Humain.

Aperçu rapide pour MME anticorps (ABIN120746)

Antigène: MME (Membrane Metallo-Endopeptidase (MME))

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp MME est non-conjugé

Application: Flow Cytometry (FACS)

Clone: LT10

Détail du produit anti-MME anticorps

Specificité: The antibody LT10 reacts with CD10 antigen (CALLA - Common acute lymphatic leukemia antigen), a 100 kDa type II integral membrane protein.

Purification: Precipitation methods and ion exchange chromatography

Pureté: > 95 % (by SDS-PAGE)

Immunogène: Mouse NALM-6 leukemia pre-B cell line (tissue/cell preparation)

Isotype: IgG1

Information d'application

Indications d'application: Flow Cytometry.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Stockage

Concentration: 1.0 mg/mL

Buffer: Phosphate buffered saline (PBS) with 15 mM sodium azide, approx. pH 7.4

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C

Stockage commentaire: Store the antibody undiluted at 4-8 °C for one month or at -20 °C for longer. Avoid repeated freezing and thawing. Should this product contain a precipitate we recommend microcentrifugation before use.
Shelf Life: one year from despatch.

Date de péremption: 12 months

Détails sur MME

Antigène: MME (Membrane Metallo-Endopeptidase (MME))

Autre désignation: CD10 / Neprilysin

Classe de substances: Chemical

Sujet: CD10 (neutral endopeptidase NEP, common acute lymphocytic leukemia antigen CALLA, membrane metallo-endopeptidase MME, enkefalinase) is a 100- kDa cell surface zinc metalloprotease cleaving peptide bonds on the N-terminus of hydrophobic amino acids and inactivating multiple physiologically active peptids. CD10 is expressed on various normal cell types, including lymphoid precursor cells, germinal center B lymhocytes, and some epithelial cells, and its expression level serves as a marker for diagnostics of many carcinomas. CD10 is also a differentiation antigen for early B-lymphoid progenitors in the B-cell differentiation pathway and has a key role in regulation of growth, differentiation and signal transduction of many cellular systems.Synonyms: Atriopeptidase, CALLA, Common acute lymphocytic leukemia antigen, EPN, Enkephalinase, MME, NEP, Neutral endopeptidase, Neutral endopeptidase 24.11

ID gène: 4311

UniProt: P08473

Pathways: Signalisation RTK, Peptide Hormone Metabolism, Regulation of Systemic Arterial Blood Pressure by Hormones, Smooth Muscle Cell Migration